Mean little kitty or is she depressed?

my cat whiskers is a 6-7 year old tortil-shell female cat. when we got her as a kitten she was fine she would try and play with our older cat trixy now 9 years old. but when she turnned 3 she went evil. she would scratch and bite but then she had kittens at 4 years she calmed down but sadly 1 got ran over at the age of 8 and a half months (R.I.P pepper) and her brother (smoky) ran off but he had not been spayed.she had another kitten litter last year (socks, lily, tiger, sooty and pepsi) fine we got ride of sooty pepsi and tiger (now have good homes) she calmed down again now here is the sad part one day we let her outside for fresh air (we have trained our cats to come back by there names) she didnt come back for 2 weeks turn out someonelocked in a cole sealer for 2 weeks with no food :( she is fine now but went sico she is a fighter as in killer so she has lost a K.9 tooth she is fine though but she doesnt like being toched ever since she was 3 years old